NCT04937712

Analysis of SARS-CoV2 Urine Viral Particles and Association With Proximal Tubular Dysfunction

Molecular Characterization and Cellular Infection Capacity of Urinary Viral Particles Isolated From SARS-CoV-2 and Association With Proximal Tubular Dysfunction, in Hospitalized Patients With COVID-19

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 34 (estimated)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

The primary goal is to detect Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV2) urine viral particles in patients in intensive care units, hospitalized for coronavirus Coronavirus Disease-19 (COVID-19) infection, and correlate the presence of the virus in the urine with proximal tubular dysfunction (defined by the association of at least 2 abnormalities: tubular proteinuria, renal phosphate leak, uricosuria, normoglycemic glycosuria, amino aciduria)

Conditions

• SARS-CoV2 Infection
• Proximal Tubule Dysfunction

Interventions

Type	Name	Description
OTHER	RT-PCR SARS-COV2 in urine	proteinuria/renal phosphate leak/uricosuria/glycosuria/ aminoaciduria)

Timeline

• Start date: 2021-08-19
• Primary completion: 2022-07-01
• Completion: 2022-07-01
• First posted: 2021-06-24
• Last updated: 2021-08-30

Locations

1 site across 1 country: France