NCT04937361

Monitoring of MDRO Dynamics and Resistance Mechanisms in a University Hospital Network

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 12,000 (estimated)
• Sponsor: University of Luebeck · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Survey on the prevalence of MDRO to monitor the import of MDRO from the community. Rectal swabs will be taken and cultivated. Survey on community-onset and nosocomial bloodstream infections will be documented and strains will be isolated. For each BSI a clinical data set will be obtained (e.g. patient age, gender, date of hospitalization, antibiotic therapy). Genetic analysis of MDRO from the prevalence and BSI study. In a subset of patients the microbiome-resistome interactome will be analysed in more detail. Furthermore, the impact of infection control measures due to the Covid-19 pandemic on nosocomial BSI will be investigated.

Conditions

• MDRO

Interventions

Type	Name	Description
OTHER	rectal swab	collection of rectal swabs

Timeline

• Start date: 2021-06-23
• Primary completion: 2024-12-31
• Completion: 2025-06-30
• First posted: 2021-06-24
• Last updated: 2023-11-29

Locations

1 site across 1 country: Germany