NCT04937023

Ursodeoxycholic Acid (Udca) as a Local Drug Delivery Agent in the Treatment of Intra-bony Defects

Assessing the Clinical Efficacy of Ursodeoxycholic Acid (Udca) as a Local Drug Delivery Agent in the Treatment of Intra-bony Defects: A Clinico-radiographic Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (estimated)
• Sponsor: SVS Institute of Dental Sciences · Academic / Other
• Sex: All
• Age: 20 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate the efficacy of ursodeoxycholic acid as local drug delivery agent in intra- bony defect to achieve bone regeneration.

Detailed description

Experimental: Main treatment group the prepared UDCA gel will be injected using a syringe with blunt cannula into the defect site. Comparator: In patients allocated to control group, placebo gel will be injected in to the defect site using a syringe with blunt cannula.

Conditions

• Bone Regeneration

Interventions

Type	Name	Description
DRUG	Ursodeoxycholic acid gel	Following scaling and root planing in intrabony defects UDCA gel will be injected

Timeline

• Start date: 2021-06-11
• Primary completion: 2021-12-31
• Completion: 2022-12-30
• First posted: 2021-06-23
• Last updated: 2021-06-23

Locations

1 site across 1 country: India