Trials / Completed
CompletedNCT04935099
The Effects of a Single Dose of Wild Blueberries on Mood and Cognition in Healthy Young Adults
The Effects of a Single Dose of Wild Blueberries on Mood and Cognition in Healthy Young Adults: a Randomized, Double-blind, Placebo-controlled, Crossover Study
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 33 (actual)
- Sponsor
- University of Reading · Academic / Other
- Sex
- All
- Age
- 18 Years – 25 Years
- Healthy volunteers
- Accepted
Summary
This study aims to investigate whether consuming a drink containing powdered blueberries (equivalent to 150 g fresh fruit) can improve mood and cognition in healthy young adults. Blood biomarkers of inflammation and neurotransmitter turnover will be analyzed as well as responses to computer-based cognitive tasks designed to measure verbal memory, executive function, and emotional processing.
Detailed description
The present study will examine the psychological effects of a single dose of freeze-dried wild blueberries using a randomized, double-blind, placebo-controlled, counterbalanced, crossover design. A total of 30 healthy young adults will consume two drinks: one containing 22 g blueberry powder and the other containing 22 g matched placebo powder in counterbalanced order one week apart. The investigators will assess changes in transient mood, cognitive-emotional function, and serum biomarkers of inflammation, neuroplasticity, and monoamine metabolism from baseline to 2 hours post-ingestion.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Wild blueberry powder | 22 g freeze-dried wild blueberry (Vaccinium angustifolium) powder, mixed with 250 ml water, and served in an opaque container. |
| DIETARY_SUPPLEMENT | Placebo powder | 22 g placebo powder matched for macronutrients and flavor, mixed with 250 ml water, and served in an opaque container. |
Timeline
- Start date
- 2021-05-26
- Primary completion
- 2021-08-27
- Completion
- 2021-08-27
- First posted
- 2021-06-22
- Last updated
- 2021-09-21
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT04935099. Inclusion in this directory is not an endorsement.