Trials / Completed
CompletedNCT04932473
ALFAsleep: Exploring Cognitive and Biological Correlates of Sleep Quality and Their Potential Links With Alzheimer's Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 179 (actual)
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation · Academic / Other
- Sex
- All
- Age
- 45 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The main goal of this study is to perform a multimodal characterization of brain structural and functional changes, as well as changes in Alzheimer's disease (AD) biomarkers, as a function of sleep quality measures. Cross-sectional data will enable us to confirm and expand previous knowledge in a large and well-phenotyped population, while longitudinal data will allow us to test the hypothesis of the existence of a bidirectional relationship between sleep quality and AD.
Detailed description
The main goal of this study is to perform a multimodal characterization of brain structural and functional changes, as well as changes in Alzheimer's disease (AD) biomarkers, as a function of sleep quality measures. Cross-sectional data will enable us to confirm and expand previous knowledge in a large and well-phenotyped population, while longitudinal data will allow us to test the hypothesis of the existence of a bidirectional relationship between sleep quality and AD.
Conditions
Timeline
- Start date
- 2021-01-26
- Primary completion
- 2022-09-20
- Completion
- 2025-05-27
- First posted
- 2021-06-21
- Last updated
- 2025-05-31
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT04932473. Inclusion in this directory is not an endorsement.