Trials / Completed
CompletedNCT04929418
Differential Adaptation of Renal Function in Intense Physical Exercise
Differential Adaptation of Renal Function in Two Types of Intense Physical Exercise
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Hospital Clínico Universitario de Valladolid · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
In recent years there has been a significant increase in the number of participants in high intensity and duration sports events. This type of physical exercise has been reported to lead to an apparently transitory deterioration in kidney function. The injury mechanisms involved in this process have not been fully studied, but several have been proposed as potential causes, such as tissue ischemia, disruption of the permeability of the glomerular basement membrane, damage to the ultra-structure of skeletal muscle, structural involvement of the renal parenchyma, exercise-associated hyperthermia or insufficient hydration during exercise. Urinary biomarkers, which are a more precise tool than serum creatinine when it comes to detecting subclinical kidney damage, may be key to elucidate the characteristics of exercise-related kidney injury. The aim of this study is to carry out an integrative analysis of the development of exercise-associated subclinical acute kidney injury.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | 10 km continuous running | Trial participants will perform a 10 km continuous running exercise |
| OTHER | 1.5 km continuous swimming | Trial participants will perform a 1.5 km continuous swimming exercise. |
Timeline
- Start date
- 2019-01-01
- Primary completion
- 2019-12-31
- Completion
- 2020-03-20
- First posted
- 2021-06-18
- Last updated
- 2021-06-18
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT04929418. Inclusion in this directory is not an endorsement.