Trials / Completed
CompletedNCT04929366
Is Hemodialysis Associated With Cardiac Markers Change?
Effects of Hemodialysis With Cooled Dialysate on High Sensitive Cardiac Troponin I (TnI) and Brain Natriuretic Peptide (NT proBNP)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 45 (actual)
- Sponsor
- Ziv Hospital · Other Government
- Sex
- All
- Age
- 18 Years – 90 Years
- Healthy volunteers
- Not accepted
Summary
Hemodialysis (HD) triggers recurrent and cumulative ischemic insults to the brain and the heart. Cooled dialysate may have a protective effect on major organs and improve hemodynamic tolerability of dialysis. The aim of the study was to compare HD with cooled dialysate with routine dialysis in terms of hemodynamic stability and levels of high sensitivity Troponin I (hs-TnI) and N-terminal pro b-type natriuretic peptide (NTproBNP) post dialysis
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Hypothermic dialysis followed with routine dialysis | Hypothermic dialysis (35.5 degrees Celsius dialysate) followed with routine dialysis (36.5 degrees Celsius dialysate) |
| PROCEDURE | Routine dialysis followed with hypothermic dialysis | Routine dialysis (36.5 degrees Celsius dialysate) followed with hypothermic dialysis (35.5 degrees Celsius dialysate) |
Timeline
- Start date
- 2017-12-18
- Primary completion
- 2020-11-16
- Completion
- 2020-11-16
- First posted
- 2021-06-18
- Last updated
- 2021-06-18
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT04929366. Inclusion in this directory is not an endorsement.