Clinical Trials Directory

Trials / Completed

CompletedNCT04925687

Phase 1 Study of Intravitreal Autologous CD34+ Stem Cell Therapy for Retinitis Pigmentosa

Phase 1 Study of the Feasibility and Safety of Intravitreal Autologous Bone Marrow CD34+ Stem Cell Therapy for Eyes With Vision Loss From Retinitis Pigmentosa

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
4 (actual)
Sponsor
University of California, Davis · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

In this Phase 1 open-labeled prospective study, one eye of each participant with vision loss from retinitis pigmentosa will be administered intravitreal injection of autologous CD34+ stem cells harvested from bone marrow. Each participant will be examined serially for 6 months after study injection to determine safety and feasibility of this intervention.

Conditions

Interventions

TypeNameDescription
BIOLOGICALIntravitreal autologous CD34+ cellsAutologous CD34+ cells harvested from bone marrow injected intravitreal

Timeline

Start date
2021-06-01
Primary completion
2023-11-01
Completion
2023-11-01
First posted
2021-06-14
Last updated
2024-09-23

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04925687. Inclusion in this directory is not an endorsement.