NCT04924855

Immunity After COVID-19 Vaccination

Estimation of Dynamics of Humoral Immunity in COVID-19 Vaccined Health Care Workers

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: General Administration of Military Health, Tunisia · Network
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: —

Summary

The purpose of the research is to evaluate kinetic after vaccination to the COVID-19 coronavirus by measurements of specific and neutralizant antibodies for spike antigenic sequences . This work will allow us to follow the efficacy and tolerance of the vaccine over a year, to evaluate the antibody profile, their kinetics, the fraction of neutralising antibodies and will also allow us to understand the attitudes to be taken to ensure the best protection for our staff

Detailed description

Our objective is to follow the hospital staff after vaccination, for this we will include two groups of participants: G1: vaccinated staff who did not contract the virus (at the date of vaccination) and who had a serology \<0 at least at D7 of the date of vaccination dose 1 (known serological value) G2: vaccinated personnel who have contracted the virus with a PCR + and who have positive serology at least at D7 of the date of vaccination (known serological value)

Conditions

• Tunis Military Hospital Staff Vaccinated Against Covid 19

Interventions

Type	Name	Description
OTHER	Blood sampling (4 per year)	Blood sampling (4 per year)

Timeline

• Start date: 2021-07-01
• Primary completion: 2022-07-01
• Completion: 2022-08-01
• First posted: 2021-06-14
• Last updated: 2021-06-14

Locations

1 site across 1 country: Tunisia