NCT04922892

Total Parathyroidectomy With Autotransplantation Versus Total Parathyroidectomy Alone for Secondary Hyperparathyroidism

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: The Second Hospital of Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Total parathyroidectomy with autotransplantation (TPTX+AT) and Total parathyr- oidectomy alone (TPTX) are the common surgical procedures.The purpose of the study was to compare the long-term benefits of surgery between the two groups.

Detailed description

The trial was performed as a nonconfirmatory randomized controlled pilot trial with 200 patients on long-term dialysis with otherwise uncontrollable SHPT to generate data on the rate of recurrent disease within a 5-year follow-up period after TPTX or TPTX+AT. Parathyroid hormone (PTH) and calcium levels, recurrent or persistent hyperparathyroidism, parathyroid reoperations, morbidity, and mortality were evaluated during a 5-year follow-up.

Conditions

• Secondary Hyperparathyroidism;Parathyroidectomy

Interventions

Type	Name	Description
PROCEDURE	Parathyroidectomy	Total Parathyroidectomy With Autotransplantation or Total Parathyroidectomy Alone

Timeline

• Start date: 2021-06-01
• Primary completion: 2023-05-31
• Completion: 2028-05-31
• First posted: 2021-06-11
• Last updated: 2021-09-27

Locations

1 site across 1 country: China