NCT04920474

Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 99,999,999 (estimated)
• Sponsor: Center for International Blood and Marrow Transplant Research · Network
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The primary purpose of the Research Sample Repository is to make blood samples available for research studies related to histocompatibility and hematopoietic cell transplantation (HCT) or other cellular therapy. Representatives of participating centers and investigators or research groups may request access to research samples contained in the Research Sample Repository for the purpose of conducting research including: * investigating molecular explanations for histocompatibility or clinical outcomes through analysis of genomic, epigenetic, or other biomolecular data * evaluating the factors that affect transplant or cellular therapy outcome * studying the distribution of HLA tissue types in different populations * studying the success of transplantation, cellular therapies or supportive care in the management of marrow toxic injuries * performing de-linked (anonymous) research

Detailed description

Research samples will be accepted from the following four categories: * Hematopoietic Cell or other Cellular Therapy Donors * Cord Blood Units * Hematopoietic Cell Transplantation or other Cellular Therapy Recipients * Patients with Marrow Toxic Injury

Conditions

• Autologous Stem Cell Transplantation
• Allogeneic Stem Cell Transplantation
• Cellular Therapy
• Marrow Toxic Injury

Timeline

• Start date: 1991-07-01
• Primary completion: 2030-07-01
• Completion: 2030-07-01
• First posted: 2021-06-09
• Last updated: 2023-05-03

Locations

1 site across 1 country: United States