Trials / Unknown
UnknownNCT04917978
Association of Hb F Level With Clinical Severity of Beta Thalassemia
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 1,200 (estimated)
- Sponsor
- Nanfang Hospital, Southern Medical University · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The production of Hb F after birth is an important factor in modifying the clinical severity of beta thalassemia because an increased gamma-globin level will bind the additional a-globin and form Hb F. The objective of this project is to evaluate the association of Hb F level with phenotypic diversity of patients with beta thalassemia.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Hematological Phenotype Analysis | Hematological parameters were determined with an automated hematology analyzer (Sysmex, Japan), and hemoglobin analysis was performed with either high-performance liquid chromatography (Bio- Rad, USA) or capillary electrophoresis (Sebia, France and Helena, USA). |
Timeline
- Start date
- 2019-12-01
- Primary completion
- 2024-12-30
- Completion
- 2025-12-30
- First posted
- 2021-06-08
- Last updated
- 2021-06-11
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04917978. Inclusion in this directory is not an endorsement.