NCT04917289

CTC vs Radiography as the Evidence of Recurrence in Colorectal Cancer Patients

Circulating Tumor Cell vs. Radiography as the Evidence of Disease Recurrence in Colorectal Cancer Patients Whose Tumor Underwent R0 Resection

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study enrolled patients who underwent R0 resection of tumor and had elevated tumor biomarkers (CEA, CA19-9). After enroll the study, a CTC test will performed and patients who had positive CTC will be randomly assigned to two groups. The control group will continue follow-up until radiological recurrence appear, the treatment group will start treatment or change the current adjuvant regimen. First endpoint is OS. The secondary endpoint is DFS, adverse event.

Conditions

• Colorectal Cancer
• Circulating Tumor Cell

Interventions

Type	Name	Description
DRUG	Chemotherapy	Started chemotherapy or change the current adjuvant therapy

Timeline

• Start date: 2021-06-01
• Primary completion: 2023-12-01
• Completion: 2025-12-01
• First posted: 2021-06-08
• Last updated: 2021-06-08