Trials / Unknown
UnknownNCT04915105
Personal Precise Treatment on Psoriasis and Psoriatic Arthritis
Personal Precise Treatment on Psoriasis and Psoriatic Arthritis and Investigate the Mechanisms of Biological Agents Induced Systemic Lupus Erythematosus
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- Sponsor
- Taichung Veterans General Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
Part of psoriasis and psoriatic arthritis patients treated with biologics and met primary failure. Therefore, we are going to create a cell based platform to evaluate the treatment effects of different biologics on psoriasis and psoriatic arthritis patients before prescribed by physicians
Detailed description
PBMCs isolated from psoriasis and psoriatic arthritis and incubated with Group A streptococcus and different biologics for 24 hours. Cytokines expression in the culture supernatants will be measured and the data can be reference for physician's prescription.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Markers data from PBMCs | Prescreen markers from patient individual PBMCs treating with streptococcus and different biologics. |
Timeline
- Start date
- 2021-05-31
- Primary completion
- 2025-05-31
- Completion
- 2025-05-31
- First posted
- 2021-06-07
- Last updated
- 2021-06-07
Source: ClinicalTrials.gov record NCT04915105. Inclusion in this directory is not an endorsement.