NCT04910620

The Evaluation of TCI378 and TCI507 Probiotics on Weight-lowering Efficacy in Adults

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 96 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Obesity is a serious global public health issue. Many reports have showed that the use of appropriate probiotics can bring benefits to the health of the host and promote the balance of gut microbiota. Clinical experimental data show that the supplement of probiotics can help regulate gut function and weight control, and etc. TCI378 (Lactobacillus plantarum TCI378) is a probiotic extracted from Korean kimchi, and TCI507 (Lactobacillus plantarum TCI507) is a probiotic extracted from the oranges peels. These two strains of probiotics have been verified by in vitro experiments to have the effect of hydrolyzing bile salts, inhibition of the production of fat cells. Therefore, we want to evaluate whether the probiotics TCI308 and TCI507 have effects on reduction of body weight.

Conditions

• Weight Reduction

Interventions

Type	Name	Description
DRUG	Placebo	Placebo only
DRUG	TCI378	TCI378 (Lactobacillus plantarum TCI378)
DRUG	TCI507	TCI507 (Lactobacillus plantarum TCI507)

Timeline

• Start date: 2021-06-15
• Primary completion: 2024-06-14
• Completion: 2024-06-14
• First posted: 2021-06-02
• Last updated: 2021-06-02