Clinical Trials Directory

Trials / Completed

CompletedNCT04906850

Evaluation of the New Variant 501Y.V2 of COVID-19

Comparison of Mortality in Severe SARS-Cov-2 Infection Caused by the 501Y.V2 Variant and B.1.1.7 Variant

Status
Completed
Phase
Study type
Observational
Enrollment
250 (actual)
Sponsor
Centre Hospitalier Régional Metz-Thionville · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

In January 2021, the incidence of COVID-19-and its mortality started rising for the third time in France. This rise may associate with three emerging variants, namely, V1, V2, and V3, which are the 20I/501Y.V1 ("English"), 20H/501Y.V2 ("South African"), and 20J/501Y.V3 ("Brazilian") variants, respectively. V1 was recently suggested to increase mortality in people in the United Kingdom who tested positive for COVID-19 on community screening. Very little is known about V2 infection, including its outcomes relative to other strains. In early 2021, V2 spread to the Grand-Est region (northeastern France). Here, the investigators aimed to report mortality data of patients admitted in ICU between February and April 2021 in 3 hospitals in Grand-Est: Metz, Thionville and Nancy.

Conditions

Timeline

Start date
2021-03-01
Primary completion
2021-04-15
Completion
2021-05-15
First posted
2021-05-28
Last updated
2021-06-02

Locations

2 sites across 1 country: France

Source: ClinicalTrials.gov record NCT04906850. Inclusion in this directory is not an endorsement.

Evaluation of the New Variant 501Y.V2 of COVID-19 (NCT04906850) · Clinical Trials Directory