Trials / Recruiting
RecruitingNCT04903223
Liver Adiposity Effects on Pediatric Statin
Effects of Pediatric Liver Adiposity on Statin Disposition and Response
- Status
- Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Children's Mercy Hospital Kansas City · Academic / Other
- Sex
- All
- Age
- 8 Years – 21 Years
- Healthy volunteers
- Accepted
Summary
Single center, open-label, prospective investigation to quantify the effects hepatocellular fat has on hepatic statin transport and response in children and adolescents in obese and non-obese children and adolescents 8-21 years of age with normal, wild-type SLCO1B1 c.521TT genotype that are dosed rosuvastatin
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Rosuvastatin 10mg | Rosuvastatin will be administered to all participants on Study Day #2 |
Timeline
- Start date
- 2021-04-01
- Primary completion
- 2026-06-30
- Completion
- 2026-12-31
- First posted
- 2021-05-26
- Last updated
- 2025-11-26
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04903223. Inclusion in this directory is not an endorsement.