NCT04901065

Xylocaine to Freeze During Unpleasant Nasopharyngeal Swabs

Xylocaine to Freeze During Unpleasant Nasopharyngeal Swabs: a Randomized, Double-Blinded, Placebo Controlled-Trial

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 88 (actual)
• Sponsor: Evelyne D.Trottier · Academic / Other
• Sex: All
• Age: 8 Years – 17 Years
• Healthy volunteers: Not accepted

Summary

Since the beginning of the COVID-19 pandemic, nasopharyngeal swabs (NPS) have been recommended to detect the virus. This procedure has been reported to be painful by 85% of children The aim of the study was to assess whether pretreatment with topical lidocaine reduces the discomfort experienced by children during a nasopharyngeal swab. This was a RCT among children aged 8-17 years old who need a NPS. The primary outcome was pain intensity as measured by the Visual Analog Scale .

Conditions

• Covid19

Interventions

Type	Name	Description
DRUG	Xylocaine	The study intervention was the administration of 10 mg of intranasal lidocaine in one nostril using 1 spray of 0.1mL of a 10% lidocaine solution 5 minutes before NPS. This was done using the standard long nozzle
DRUG	Placebo	The control group received the placebo with the same application technique using an empty bottle of lidocaine 10% with the same long nozzle for delivery

Timeline

• Start date: 2021-05-11
• Primary completion: 2021-06-07
• Completion: 2021-06-07
• First posted: 2021-05-25
• Last updated: 2021-09-27

Locations

1 site across 1 country: Canada