NCT04899011

Taste Disturbance After Middle Ear Surgery: Frequency, Duration, Influence of Chorda Tympani Injury and Quality of Life

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 214 (actual)
• Sponsor: Centre Hospitalier Universitaire de Nice · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Chorda tympani nerve (CTN), is a branch of nerve VII, and has two componants: taste sensation from the anterior two thirds of the tongue and salivary secretion from submandibular and sublingual salivary glands. CTN go throw middle ear between malleus and incus. Due to it anatomic localization, CTN is frequently damage during otologic surgery. Taste disturbance after middle ear surgery has been describe in literature but results of the various studies are very heterogenous. Moreover, there is no consensus to preserved or sacrificed a traumatize CTN. We will use questionnaire to evaluate frequency, duration and characteristics of taste disturbance after ear surgery and the impact on the quality of life for those with symptoms. We will evaluate the Influence of type of CTN injury on taste disturbance.

Conditions

• Ear Middle Problems

Interventions

Type	Name	Description
OTHER	Questionnaire	Questionnaire about taste and salivary disturbance before surgery, 10 days, 4 months and 1 year after surgery. Questionnaires include characteristics of taste disturbance, and specific impact on quality of life.

Timeline

• Start date: 2021-05-30
• Primary completion: 2023-05-23
• Completion: 2023-05-23
• First posted: 2021-05-24
• Last updated: 2025-03-10

Locations

1 site across 1 country: France