Clinical Trials Directory

Trials / Recruiting

RecruitingNCT04896684

Chronic Intestinal Pathologies Analytical Cohort at TouLouse

Status
Recruiting
Phase
Study type
Observational
Enrollment
300 (estimated)
Sponsor
University Hospital, Toulouse · Academic / Other
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

In the general population, the percentage of people with at least one digestive disease is 16.7%. Among these digestive diseases, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and patients who should benefit from digestive examinations as part of a screening oriented either by the patient's family history or following the performance of an immunological screening test ( FIT) in the stool will be studied. The aim of this project is to build a biological collection with associated clinical data for research projects.

Detailed description

In the general population, the percentage of people with at least one digestive disease is 16.7%. Among these digestive diseases, two of them namely inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) will be more particularly studied. This interest is based on the increasing frequency of these two pathologies, their chronicities but above all the limited physiopathological data available. In addition, it seems interesting to study a third population, namely patients who should benefit from digestive examinations as part of a screening oriented either by the patient's family history or following the performance of an immunological screening test ( FIT) in the stool. The study of this population is part of an improvement in knowledge on the carcinogenesis of colorectal cancer. To study these populations, blood, serum, plasma and tissues from colonous biopsies or surgical samples will be collected. This cohort will make it possible to study, among other things, the pathophysiology of chronic diseases of the small intestine and the colon (IBD, IBS, screening) in order to improve their management through the development of new biomarkers and therapeutic targets.

Conditions

Interventions

TypeNameDescription
BIOLOGICALblood and intestinal biopsy sampling24 mL of blood and 10 intestinal biopsies will be sampled

Timeline

Start date
2021-04-29
Primary completion
2025-09-01
Completion
2025-09-01
First posted
2021-05-21
Last updated
2024-06-28

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT04896684. Inclusion in this directory is not an endorsement.