Clinical Trials Directory

Trials / Completed

CompletedNCT04896385

A Study to Evaluate the Mechanism of Action of Ruxolitinib Cream in Subjects With Vitiligo (TRuE-V MOA)

A Randomized, Double-Blind, Vehicle-Controlled Study to Evaluate the Mechanism of Action of Ruxolitinib Cream for Vitiligo

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
60 (actual)
Sponsor
Incyte Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to evaluate the Mechanism Of Action (MOA) of ruxolitinib cream in vitiligo by assessing the change in biomarkers.

Conditions

Interventions

TypeNameDescription
DRUGRuxolitinib creamRuxolitinib cream is a topical formulation applied as a thin film to affected areas.
DRUGVehicle CreamVehicle cream is matching in appearance to ruxolitinib cream and is to be applied in the same manner as ruxolitinib cream.

Timeline

Start date
2021-06-23
Primary completion
2022-11-17
Completion
2023-07-10
First posted
2021-05-21
Last updated
2025-08-05
Results posted
2023-12-07

Locations

13 sites across 3 countries: United States, Canada, France

Regulatory

Source: ClinicalTrials.gov record NCT04896385. Inclusion in this directory is not an endorsement.