NCT04895462

Acute Revascularization Treatment in Ischemic Stroke Patients With COVID-19

Safety and Outcomes of Acute Revascularization Treatment in COVID Patients: an International Comparative Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 15,128 (actual)
• Sponsor: Centre Hospitalier Universitaire Vaudois · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Case-series and cohort studies have shown the feasibility of reperfusion therapies in patients with ischemic stroke and COVID-19, but due to the absence of a contemporary control group of non-COVID-19 patients, small sample size or lack of long-term outcome assessment, concerns regarding safety and efficacy of these treatments remain to be clarified. Taking into account its limitations, some studies documented higher rates of endovascular treatment complications such as clot fragmentation with distal embolization and vessel re-oclusion, to be more difficult to achieve recanalization after endovascular treatment, and higher rates of any intracerebral hemmorhage. The investigators aim is to assess in a large, multicenter and international cohort, the safety and outcomes of acute reperfusion therapies in patients with ischemic stroke and COVID-19, by comparison with a contemporary control group of patients with ischemic stroke and without COVID-19 from the same centers.

Conditions

• Ischemic Stroke
• Covid19

Timeline

• Start date: 2021-04-30
• Primary completion: 2021-08-31
• Completion: 2021-10-30
• First posted: 2021-05-20
• Last updated: 2023-03-08

Locations

1 site across 1 country: Switzerland