Clinical Trials Directory

Trials / Completed

CompletedNCT04894305

A Study of Ad26.COV2.S in Healthy Adults (COVID-19)

A Phase 1, Randomized, Observer-blind Study to Compare the Safety, Reactogenicity, and Immunogenicity of Ad26.COV2.S at a Single Dose of 5*10^10 vp in 2 Different Volumes in Healthy Adults

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
380 (actual)
Sponsor
Janssen Vaccines & Prevention B.V. · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess the safety and reactogenicity of Ad26.COV2.S (0.3 milliliter \[mL\] versus 0.5 mL) and to demonstrate non-inferiority (NI) of Ad26.COV2.S (0.3 mL versus 0.5 mL), 28 days after vaccination.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAd26.COV2.SAd26.COV2.S will be administered as IM injection.

Timeline

Start date
2021-05-25
Primary completion
2021-12-08
Completion
2021-12-08
First posted
2021-05-20
Last updated
2021-12-22

Locations

1 site across 1 country: Netherlands

Regulatory

Source: ClinicalTrials.gov record NCT04894305. Inclusion in this directory is not an endorsement.