NCT04894019

Effect of Continuous Invasive Blood Pressure Monitoring on Postinduction Hypotension in Patients Having Major Surgery

The Effect of Continuous Invasive Arterial Blood Pressure Monitoring on Postinduction Hypotension in Patients Having Major Surgery (AWAKE Trial): a Randomized Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 242 (actual)
• Sponsor: Universitätsklinikum Hamburg-Eppendorf · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized trial (1) investigating whether continuous invasive arterial blood pressure monitoring using an arterial catheter reduces the area under a mean arterial pressure (MAP) of 65 mmHg within the first 15 minutes of anesthetic induction compared to intermittent arterial blood pressure monitoring using oscillometry in patients having major surgery under general anesthesia; and (2) investigating the effect of continuous invasive arterial blood pressure monitoring using an arterial catheter on cardiac output, stroke volume, and heart rate within the first 15 minutes of anesthetic induction compared to intermittent blood pressure monitoring using upper-arm cuff oscillometry in patients having major surgery under general anesthesia.

Detailed description

not provided

Conditions

• Blood Pressure
• Perioperative Hypotension
• Postinduction Hypotension

Interventions

Type	Name	Description
DEVICE	Continuous invasive blood pressure monitoring	Continuous invasive blood pressure monitoring using an arterial catheter
DEVICE	Intermittent non-invasive blood pressure monitoring	Intermittent non-invasive blood pressure monitoring using upper-arm cuff oscillometry

Timeline

• Start date: 2021-05-16
• Primary completion: 2021-11-23
• Completion: 2021-11-23
• First posted: 2021-05-20
• Last updated: 2021-12-03

Locations

1 site across 1 country: Germany