NCT04890782

Gut Microbiota in Patients With Moyamoya Disease

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: Beijing Tiantan Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study is to find out the association between gut microbiota and moyamoya disease.

Detailed description

Moyamoya disease (MMD) is a rare cerebrovascular disorder, it is a major cause of stroke in children and young adults in Japan, Korea, and China, but its pathogenesis is not yet clear. Dysbiosis of gut microbiota may play a role in the pathological change of MMD. In this research, the investigators would perform metagenomic sequencing to find the characteristics of gut microbiota of MMD and to explore the correlations with metabolic, immune, and clinical symptoms. This research will not only help the understanding of the pathophysiology of MMD, but also may provide a reference for the selection of clinical treatment options.

Conditions

• Moyamoya Disease
• Gut Microbiota

Timeline

• Start date: 2021-05-01
• Primary completion: 2021-12-31
• Completion: 2021-12-31
• First posted: 2021-05-18
• Last updated: 2021-05-18

Locations

1 site across 1 country: China