Trials / Completed
CompletedNCT04890626
Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19
Randomized Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 356 (actual)
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Currently COVID-19 is an international public health emergency. Most COVID-19 patients have mild or uncomplicated disease, but approximately 14% develop severe disease that requires hospitalization and oxygen therapy, and up to 5% of patients require admission to Intensive Care Units. To date, the only treatments that have shown efficacy in a clinical trial are remdesivir and dexamethasone. The main objective is to provide reliable estimates on the effects of different treatment strategies on the outcome and mortality of patients with SARS-CoV-2 infection.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Emtricitabine/Tenofovir Disoproxil Fumarate 200 MG-245 MG Oral Tablet [TRUVADA] | Main randomization |
| DRUG | Baricitinib + dexamethasone | Rescue randomization |
| DRUG | Dexamethasone | Rescue randomization |
Timeline
- Start date
- 2020-04-04
- Primary completion
- 2023-07-17
- Completion
- 2023-07-17
- First posted
- 2021-05-18
- Last updated
- 2024-03-06
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT04890626. Inclusion in this directory is not an endorsement.