Trials / Completed
CompletedNCT04889690
Study of Multiple Doses of Danicopan in Healthy Participants
A Multiple Ascending Dose Study To Assess Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of ACH-0144471 In Healthy Volunteers
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 45 (actual)
- Sponsor
- Alexion Pharmaceuticals, Inc. · Industry
- Sex
- All
- Age
- 25 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This was a multiple ascending dose, randomized, double-blind study assessing the safety, tolerability, pharmacokinetics, and pharmacodynamics of danicopan in healthy participants. Four different doses (75 milligrams \[mg\], 200 mg, 500 mg, 800 mg) and dose-matched placebo were administered under fasted conditions.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Danicopan | |
| DRUG | Placebo |
Timeline
- Start date
- 2016-05-21
- Primary completion
- 2017-01-11
- Completion
- 2017-01-11
- First posted
- 2021-05-17
- Last updated
- 2021-05-17
Locations
1 site across 1 country: New Zealand
Source: ClinicalTrials.gov record NCT04889690. Inclusion in this directory is not an endorsement.