Trials / Completed
CompletedNCT04889677
Study of a Single Dose of Danicopan in Healthy Participants
A Single Ascending Dose Study To Assess The Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Of ACH 0144471 In Healthy Volunteers
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 44 (actual)
- Sponsor
- Alexion Pharmaceuticals, Inc. · Industry
- Sex
- All
- Age
- 21 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This was a single ascending dose, randomized, double-blind study assessing the safety, tolerability, pharmacokinetics, and pharmacodynamics of danicopan in healthy participants. Four different doses (200 milligrams \[mg\], 600 mg, 1200 mg, 2400 mg) and dose-matched placebo were administered under fasted and fed conditions.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Danicopan | |
| DRUG | Placebo |
Timeline
- Start date
- 2016-02-04
- Primary completion
- 2016-06-21
- Completion
- 2016-06-21
- First posted
- 2021-05-17
- Last updated
- 2021-05-17
Locations
1 site across 1 country: New Zealand
Source: ClinicalTrials.gov record NCT04889677. Inclusion in this directory is not an endorsement.