NCT04886882

Topical Agents Containing Magnesium Sulfate & Wound Healing in the Rat Model

The Effect of Topical Agents in Cream Formations Containing Magnesium Sulfate on Wound Healing in the Rat Model

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Başakşehir Çam & Sakura City Hospital · Other Government
• Sex: Female
• Age: 8 Weeks – 12 Weeks
• Healthy volunteers: Accepted

Summary

An experimental study examining wound healing in 5 different groups on 30 rats.

Detailed description

Magnesium topically increases collagen synthesis and angiogenesis, providing faster and higher quality wound healing. In addition, with its analgesic effect, it will also eliminate the pain sensation caused by the wound and increase the quality of life of the patient whose skin integrity is impaired.

Conditions

• Wound Heal

Interventions

Type	Name	Description
OTHER	placebo comparator	solution containing 0.9 % sodium chlorine
OTHER	sham comparator	vaseline, beeswax,polyglyceryl-3 diisostearate, sorbitan caprylate, propandiol,benzoic acid, glycerin, water
OTHER	Experimental drug 1	A cream containing 10 % MgSO4.vaseline, beeswaxpolyglyceryl-3 diisostearate, sorbitan caprylate, propandiol,benzoic acid, glycerin, water
OTHER	Experimental drug 2	A cream containing 10 % MgSO4.vaseline, beeswax,polyglyceryl-3 diisostearate, sorbitan caprylate, propandiol,benzoic acid, glycerin, water
DRUG	Centella asiatica	A cream containing Centella asiatica

Timeline

• Start date: 2021-03-22
• Primary completion: 2021-06-01
• Completion: 2021-07-01
• First posted: 2021-05-14
• Last updated: 2021-05-14

Locations

1 site across 1 country: Turkey (Türkiye)