NCT04886089

Pleth Variability Index as a Predictor for Post-induction Hypotension in Elderly Patients

Pre-anesthesia Pleth Variability Index as a Predictor for Post-induction Hypotension in Elderly Patients Undergoing General Anesthesia: A Prospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 85 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 65 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Hypotension after induction of general anesthesia and before surgical stimulation is a prevalent anesthesia-related side effect. The post-induction hypotension disrupts organ perfusion and may cause organ damage particularly acute kidney injury, cerebrovascular stroke, and myocardial ischemia. Post-induction hypotension occurs with greater frequency and severity in the elderly. This is because of aged-related diminished cardiac reserve and impaired autonomic homeostasis. Pleth variability index (PVI) is a software program that measures the dynamic changes of the PI that occurs during a complete respiratory cycle. Our primary outcome is to determine the predictive ability and the optimal cut-off value of pre-anesthesia PVI for predicting elderly patients who are at risk of developing post-induction hypotension

Conditions

• Post-induction Hypotension

Interventions

Type	Name	Description
DEVICE	Pleth variability index for prediction of post-induction hypotension	The use of the baseline Pleth variability index values for prediction of occurrence of post-induction hypotension

Timeline

• Start date: 2021-08-01
• Primary completion: 2023-08-01
• Completion: 2025-01-01
• First posted: 2021-05-13
• Last updated: 2025-04-08

Locations

1 site across 1 country: Egypt