NCT04884893

Effect of Nitrous Oxide on EEG

The Effect of Nitrous Oxide on EEG, a Randomized, Double-blinded Study

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Tampere University Hospital · Academic / Other
• Sex: Male
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Our recent preclinical observations suggest that monitoring of slow electroencephalogram (EEG) oscillations may be used to predict the efficacy of rapid-acting antidepressants such as ketamine or nitrous oxide. In this project we will carry out critical clinical research on healthy volunteers and study the effects of nitrous oxide on EEG. Results will be used for the design of clinical trials on depressed individuals. The project will be done in collaboration between neuroscientists at the University of Helsinki and clinicians at the Tampere University Hospital.

Conditions

• Nitrous Oxide
• Electroencephalography
• Anesthetic, Inhalation

Interventions

Type	Name	Description
DRUG	Nitrous Oxide	50% nitrous oxide

Timeline

• Start date: 2021-05-21
• Primary completion: 2021-09-24
• Completion: 2021-09-24
• First posted: 2021-05-13
• Last updated: 2021-12-10

Locations

1 site across 1 country: Finland