Trials / Completed
CompletedNCT04884464
Hyaluronic Acid in Counteracting Aphthous Stomatitis
Clinical Evaluation of a Hyaluronic Acid-based Medical Device in Counteracting Aphthous Stomatitis in Adults
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 49 (actual)
- Sponsor
- University of Urbino "Carlo Bo" · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Oral mucosal ulcers can determine a real worsening of the quality of life. Conventional therapy usually lasts not less than 2-3 weeks, and carries a high risk of serious side effects; furthermore, ulcers often recur. The use of hyaluronic acid applied as an adhesive gel over the lesions seems to have potential in terms of efficacy and the avoidance of side effects. Of course, hyaluronic acid-based formulations show different effects and tolerability. In this retrospective observational study, the results obtained using a hyaluronic-acid based medical device applied for 14 days to counteract ulcers in adults will be reported.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Hyaluronic acid-based gel | Dosage: application of an even coat of 1mm thickness Frequency: 3 times/day (after main meals) Duration: 2 weeks |
| DRUG | Chlorhexidine Gluconate | Dosage: application of an even coat of 1mm thickness Frequency: 3 times/day (after main meals) Duration: 2 weeks |
Timeline
- Start date
- 2018-09-01
- Primary completion
- 2019-06-30
- Completion
- 2019-06-30
- First posted
- 2021-05-13
- Last updated
- 2021-07-22
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT04884464. Inclusion in this directory is not an endorsement.