Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT04882254

Normothermic Machine Perfusion: an Additional Value for Kidney Transplant Outcomes?

Normothermic Machine Perfusion as Additional Value to Hypothermic Machine Perfusion for Kidney Transplant Outcomes. A Single-centre, Open-label, Randomised, Controlled Trial.

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
80 (actual)
Sponsor
Erasmus Medical Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is a randomised, controlled, phase II trial to assess the efficacy of 2 hours normothermic machine perfusion (NMP) of extended criteria(EC)-DBD (donation after brain death) and DCD (donation after circulatory death) donor kidneys compared to standard care, which is hypothermic machine perfusion (HMP) only in the Netherlands.

Conditions

Interventions

TypeNameDescription
PROCEDURENormothermic machine perfusionAdditional 2h of normothermic machine perfusion of the donor kidney with a red cell based perfusate.

Timeline

Start date
2021-05-01
Primary completion
2024-05-06
Completion
2025-05-01
First posted
2021-05-11
Last updated
2024-05-07

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT04882254. Inclusion in this directory is not an endorsement.