NCT04881253

COVID-19 Patient Cohort: Retinal Damage in Non-invasive Retinal Imaging (OCTA)

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 23 (actual)
• Sponsor: Centre Hospitalier Intercommunal Creteil · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this research is to build a collection of non-invasive retinal imaging (OCT and OCTA) in order to investigate the incidence and impact of retinal damage in patients who have or have had COVID-19.

Detailed description

This monocentric study is aimed at 3 types of patients: * Those who have been hospitalized for Covid-19 during the epidemic * Newly infected and diagnosed patients Covid-19 * Those with paucisymptomatic Covid-19 who did not require hospitalisation At the patient's inclusion, an ophthalmologic assessment will be performed including : * visual acuity, * SD-OCT + multicolor, * OCT-A, * color retinography, Fundus examination, optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in all COVID-19 patients may detect retinal lesions. In addition, if a correlation is demonstrated between clinical and paraclinical parameters and between disease severity and retinal vascular damage in non-invasive imaging (OCT and OCTA), this would allow a better understanding of the pathophysiology of the disease, as well as factors that may influence disease severity and the mechanisms potentially responsible for the observed disorders.

Conditions

• Covid19
• Retina Injury

Timeline

• Start date: 2021-11-05
• Primary completion: 2023-01-17
• Completion: 2023-01-17
• First posted: 2021-05-11
• Last updated: 2025-09-02

Locations

1 site across 1 country: France