NCT04878679

Effect of WB-EMS on Parkinson's Disease

Effects of Combined Whole Body Electromiostimulation (WB-EMS) and Dynamic Movements on Motor and Cognitive Performance, Neurotrophic Factors and Alpha-synuclein in Parkinson's Disease

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (estimated)
• Sponsor: Università degli studi di Roma Foro Italico · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The aim is to establish adequate and suitable protocols for PD patients and to determine the WB-EMS effects on muscle strength, balance, walking, cognitive functions,neurotrophic factors and alpha-synuclein. Thirty-six PD patients, aged from 50 to 80 years, will be recruited and randomly assigned to two experimental groups (EGs and EGc) and one control group (CG), in order to perform dynamic movements with WB-EMS. EGs will undergo to 12-20 minutes of progressive supervised WB-EMS (4 sec. 85 HZ and 4 sec. rests) combined to light dynamic movements, two-time per week for 12/24 weeks. EGe will undergo to 12-20 minutes of progressive supervised WB-EMS 7 Hz) combined with cardiovascular training with rowing machine. CG will not perform any type of physical activity. Pre and post intervention assessment will be carried out on the following areas: physical assessment, neurocognitive, neurotrophic factors and alpha-synuclein assesments. A 3 months follow-up will be performed.

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
OTHER	Strenght training combined with WB-EMS	Bodyweight exercise training combined with WB-EMS (2 times/week) with a 85Hz electrical impulse
OTHER	Cardiovascular training with WB-EMS	Cardiovascular training , using the rowing machine, combined with WB-EMS (2 times/week) with a 7Hz electrical impulse
OTHER	Control group	No physical activity

Timeline

• Start date: 2021-04-15
• Primary completion: 2022-09-23
• Completion: 2023-04-30
• First posted: 2021-05-07
• Last updated: 2023-05-11

Locations

1 site across 1 country: Italy