NCT04865211

Does a ThoracoLumbar Interfacial Plane (TLIP) Block With Liposomal Bupivacaine Provide TLIP Block in Spinal Surgery

Does a ThoracoLumbar Interfacial Plane (TLIP) Block With Liposomal Bupivacaine Provide Extended Post-operative Analgesia Following Spinal Surgery

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: The Cooper Health System · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The investigators are looking to recruit patients into a study demonstrating the effectiveness of a superficial nerve block involving the thoracolumbar interfascial plane (TLIP) in reducing postoperative pain in those undergoing spinal surgery

Detailed description

Patients undergoing spine surgery with or without fusion experience a great deal of pain especially in the first 3 days after surgery. Spine surgeons are looking for ways to reduce the pain that you experience. Anesthesiologists have introduced a procedure, called a "TLIP block" to provide pain relief. The block involves injecting local anesthetic (numbing pain medication) in the lower back around the site of the surgery. This block has been used by other surgeons for other types of surgeries in the past and has been shown to work. To determine how effective the block is, the investigators are conducting this investigational study where pain severity in patients who receive one of 2 kinds of local anesthetic or placebo are compared

Conditions

• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	Liposomal bupivacaine	Use of liposomal bupivicaine as intraoperative local anesthesia
DRUG	Bupivacaine Injection	Use of bupivicaine as intraoperative local anesthesia
DRUG	Placebo	Use of saline as placebo for local anesthesia

Timeline

• Start date: 2021-04-05
• Primary completion: 2022-02-17
• Completion: 2022-04-30
• First posted: 2021-04-29
• Last updated: 2021-04-29

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study