NCT04864899

Clinical Significance of Subclinical Myocardial Involvement in Recovered COVID-19 Patients Using Cardiovascular Magnetic Resonance (R-COVID-CMR)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 112 (actual)
• Sponsor: The University of Hong Kong · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This is a prospective cohort study that aims to clinical significance of subclinical myocardial involvement in recovered COVID-19 patients using cardiovascular magnetic resonance.

Detailed description

This study aims to: 1. Determine the extent of myocardial involvement of COVID-19, as assessed by Cardiovascular Magnetic Resonance (CMR), 2 weeks after patient recovery, at 3-month post discharge and at 1-year post discharge. 2. Correlate these myocardial characteristics to biventricular structure, function, blood biomarkers of inflammation, clinical symptoms, and functional capacity at all time points. 3. Follow up recovered COVID-19 patients beyond the end of this study to assess for hard outcomes such as death, heart failure hospitalization, cardiac arrest and ventricular tachycardia/ fibrillation. Recovered COVID-19 patients and age and gender matched controls subjects will be recruited.

Conditions

• Covid19
• Viral Respiratory Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cardiac Magnetic Resonance Imaging (CMR)	Imaging
DIAGNOSTIC_TEST	Blood test	Blood investigation
DIAGNOSTIC_TEST	6-minute walk test	Correlating the cardiac MRI parameters with functional capacity

Timeline

• Start date: 2021-09-01
• Primary completion: 2024-08-06
• Completion: 2024-08-06
• First posted: 2021-04-29
• Last updated: 2025-05-11

Locations

1 site across 1 country: Hong Kong