Trials / Active Not Recruiting
Active Not RecruitingNCT04859296
AnalgeSiC and appEtite-stimulating Effects of caNnabigerol and THC (ASCENT)
Analgesic and Appetite-stimulating Effects of Cannabigerol Administered Alone and in Combination With Delta-9-tetrahydrocannabinol
- Status
- Active Not Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- University of California, Los Angeles · Academic / Other
- Sex
- All
- Age
- 21 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This study will assess the analgesic, appetite-stimulating, and subjective effects of cannabigerol (CBG) alone and in combination with THC.
Detailed description
The overall aim of this double-blind, placebo-controlled, within-subject study in healthy, occasional cannabis smokers is to ascertain the dose-dependent analgesic and appetite-stimulating effects of ecologically relevant doses of cannabigerol (CBG) alone and in combination with a sub-analgesic / sub-appetite stimulating, minimally psychoactive dose of THC and an analgesic, appetite-stimulating, but intoxicating dose of THC.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Placebo | Vaporized placebo |
| DRUG | Low CBG | Vaporized CBG (5 mg) |
| DRUG | High CBG | Vaporized CBG (15 mg) |
| DRUG | Low THC | Vaporized THC (5 mg) |
| DRUG | High THC | Vaporized THC (15 mg) |
Timeline
- Start date
- 2023-02-15
- Primary completion
- 2025-12-04
- Completion
- 2026-12-04
- First posted
- 2021-04-26
- Last updated
- 2026-03-20
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04859296. Inclusion in this directory is not an endorsement.