NCT04858880

Personalized Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy.

Personalized Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy: a Randomized Phase III Study.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 374 (estimated)
• Sponsor: Lund University Hospital · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

A randomized phase III trial to study the effect of adding lymph node irradiation in patients with poor prostate-specific antigen (PSA) response during salvage radiotherapy for biochemical recurrence (0.15 ≤ PSA \<0.70 ng/ml) after prostatectomy.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
RADIATION	Radiation to the prostate bed with or without addition of radiation of lymph node irradiation.	Radiation to the prostate bed with or without addition of radiation of lymph node irradiation (non responders). Patients with PSA response continues radiotherapy as initially planned, and are not followed according to the study protocol, only according to clinical practice.

Timeline

• Start date: 2021-04-09
• Primary completion: 2030-04-01
• Completion: 2030-04-01
• First posted: 2021-04-26
• Last updated: 2025-09-16

Locations

3 sites across 1 country: Sweden