NCT04856670

Assessing Diabetes Mellitus on Cytokine Analysis and Macular Edema Following FLACS

Assessing the Impact of Diabetes Mellitus on Anterior Chamber Cytokine Production and Postoperative Macular Edema in Patients Undergoing Femtosecond Laser-assisted Cataract Surgery

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 140 (estimated)
• Sponsor: Uptown Eye Specialists · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess the effects of diabetes mellitus (DM) on anterior chamber cytokine production and postoperative macular edema in patients undergoing femtosecond laser-assisted cataract surgery (FLACS). Patients with DM routinely undergo FLACS, yet the majority of studies evaluating intraocular inflammation following femtosecond laser treatment have excluded this patient population. Importantly, DM alters the inflammatory status of the eye, which may influence the production of inflammatory mediators following femtosecond laser treatment and the development of postoperative macular edema. The results from this study will provide insight into the risks and benefits of FLACS in patients with DM.

Detailed description

As discussed above.

Conditions

• Cystoid Macular Edema
• Diabetes Mellitus
• Cataract

Interventions

Type	Name	Description
PROCEDURE	Cataract surgery	Cataract surgery- Manual or femtosecond laser assisted

Timeline

• Start date: 2021-05-25
• Primary completion: 2021-09-15
• Completion: 2021-09-15
• First posted: 2021-04-23
• Last updated: 2021-05-12

Locations

1 site across 1 country: Canada