NCT04856319

The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant Success

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Biruni University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

There is no consensus on antibiotic prophylaxis in dental implant applications, and its necessity is controversial. Current reports on antibiotic use are insufficient. Also, other than antibiotic prophylaxis, data that may affect the post-operative situation such as the patient's gender, age, smoking, duration of surgery, length of the operation field, flap design have not been evaluated comprehensively. This study aims to evaluate post-operative complications, implant success, and implant stability in 50 individuals: preoperative single dose of 2 g amoxicillin + clavulanic acid (25) and placebo (25).

Conditions

• Tooth Loss

Interventions

Type	Name	Description
PROCEDURE	Dental implant placement	Insertion of not more than two dental implants at the same area
DRUG	Antibiotic prophylaxis	Per-os 2g amoxicillin+clavulanic acid will be administered one hour prior to the surgery
OTHER	Placebo	Per-os placebo (inert polysaccharide) will be administered one hour prior to the surgery

Timeline

• Start date: 2022-09-01
• Primary completion: 2023-09-01
• Completion: 2023-12-01
• First posted: 2021-04-23
• Last updated: 2023-08-30

Locations

1 site across 1 country: Turkey (Türkiye)