Clinical Trials Directory

Trials / Completed

CompletedNCT04855305

Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
46 (actual)
Sponsor
Bastiaan Driehuys · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The purpose of this multi-centered, NIH-sponsored study is to to develop an optimal protocol for using noninvasive 129Xe gas exchange MRI to detect changing disease activity in interstitial lung diseases (ILDs).

Conditions

Interventions

TypeNameDescription
DRUGHyperpolarized 129XeHyperpolarized 129Xe will be administered in multiple doses in volumes that are tailored to the participant's total lung capacity (TLC) followed by a breath hold of up to 15 seconds.

Timeline

Start date
2021-11-12
Primary completion
2025-06-11
Completion
2025-06-11
First posted
2021-04-22
Last updated
2026-02-04

Locations

4 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04855305. Inclusion in this directory is not an endorsement.