NCT04853641

Impact of Age and BMI on Liver Transplant Outcomes

The Impact of Advanced Age and High BMI on Short-term Outcomes in Live-donor Liver Transplant Recipients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 700 (actual)
• Sponsor: University of Pittsburgh · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Prospectively enrolled retrospective chart review and Liver Transplant database review to determine the modifiable and nonmodifiable risk factors specifically relating to Living Donor Liver Transplants. To observe the impact of age and BMI on graft outcomes and whether they impact the intraoperative management, post-operative length of stay, and complications.

Detailed description

There has been a great deal of research into the characteristics of the donor for organ transplant, with older donors and those with more comorbidities having worse function once the organ is implanted. There has not been a great deal of research in the United States about the recipient's characteristic including age and BMI and the effects on donor organ function. With increasingly expanded criteria for organ recipients especially in the field of living donor organs the investigators plan to show the impact of older age and increased BMI on newly transplanted organs.

Conditions

• Liver Transplant; Complications
• Perioperative/Postoperative Complications

Interventions

Type	Name	Description
PROCEDURE	Cadaveric	Cadaveric Organ Transplant
PROCEDURE	Living Donor	Living Donor Organ Transplant

Timeline

• Start date: 2020-07-01
• Primary completion: 2022-06-30
• Completion: 2022-11-30
• First posted: 2021-04-21
• Last updated: 2023-04-28

Locations

1 site across 1 country: United States