Clinical Trials Directory

Trials / Terminated

TerminatedNCT04852692

A Study to Investigate the Comparative Effectiveness of Ibrutinib in Steroid Dependent/Refractory cGVHD Participants

A Retrospective/Prospective, Multicenter, Non-interventional, Historical Control Study Investigating Comparative Effectiveness of IMBRUVICA in Steroid Dependent/Refractory cGVHD Patients

Status
Terminated
Phase
Study type
Observational
Enrollment
15 (actual)
Sponsor
Janssen Korea, Ltd., Korea · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the effectiveness of ibrutinib compared to conventional salvage treatments in participants with steroid dependent/refractory chronic graft versus host disease (cGVHD) by measuring overall cGVHD response (modified National Institutes of Health \[NIH\] response defined complete response \[CR\] and partial response \[PR\]) at Week 24.

Conditions

Timeline

Start date
2021-06-21
Primary completion
2021-08-06
Completion
2021-08-06
First posted
2021-04-21
Last updated
2025-05-23

Locations

8 sites across 1 country: South Korea

Source: ClinicalTrials.gov record NCT04852692. Inclusion in this directory is not an endorsement.