Trials / Completed
CompletedNCT04850820
Impact of Amino Acids to Enhance Anabolism After Home-based Exercise
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- University of Toronto · Academic / Other
- Sex
- All
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Accepted
Summary
An adequate quantity of lean body mass is vital for optimal health and performance, and is accrued when net protein balance (NPB) is positive. Amino acids are the building blocks of protein, and when consumed following resistance exercise, significantly improve NPB. However, no study has investigated how a supplement of all of the essential amino acids (EAA) affects NPB following resistance exercise in a free-living, home-based setting, particularly when compared to a supplement of branched-chain amino acids (BCAA). Therefore, the purpose of this study is to determine the impact of a novel EAA supplement on anabolism (e.g., NPB) as compared to BCAA and placebo supplements following home-based resistance exercise.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Novel essential amino acid supplementation | This intervention will determine the impact of EAA+ on markers of whole-body net protein balance, protein synthesis, and protein breakdown following home-based resistance exercise in a free-living setting. |
| DIETARY_SUPPLEMENT | Branched-chain amino acid supplementation (BCAA) | This intervention will determine the impact of the BCAA supplement (to be compared to EAA+) on markers of whole-body net protein balance, protein synthesis, and protein breakdown following home-based resistance exercise in a free-living setting. |
| DIETARY_SUPPLEMENT | Isocaloric carbohydrate supplementation | This intervention will determine the impact of an isocaloric carbohydrate placebo supplement (to be compared to EAA+) on markers of whole-body net protein balance, protein synthesis, and protein breakdown following home-based resistance exercise in a free-living setting. |
Timeline
- Start date
- 2021-04-01
- Primary completion
- 2021-12-31
- Completion
- 2021-12-31
- First posted
- 2021-04-20
- Last updated
- 2022-05-05
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT04850820. Inclusion in this directory is not an endorsement.