NCT04849871

Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma

Evaluation of Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma - BreaStBRT

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 134 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: Female
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

This study will evaluate the local control, complication rates, cosmetic results, and quality of life between patients treated with a single fraction vs. five fractions of accelerated partial breast irradiation (S\_APBI vs. F\_APBI) when used as the sole method of radiation therapy.

Conditions

• Breast Carcinoma
• Breast Cancer
• Stage 0 Breast Cancer
• Stage I Breast Cancer

Interventions

Type	Name	Description
RADIATION	External Beam Accelerated Partial Breast Irradiation	APBI simulation must take place no more than 8 weeks from final definitive breast surgery.

Timeline

• Start date: 2021-08-12
• Primary completion: 2029-08-06
• Completion: 2029-08-06
• First posted: 2021-04-19
• Last updated: 2025-05-07

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study