Trials / Completed
CompletedNCT04848129
Genetic Correlates of Wasting: a Pilot Study With Children Attending a Tertiary Feeding Clinic
What Makes Children Thin? Genetic and Behavioural Correlates of Wasting: a Pilot Study With Children Attending a Tertiary Feeding Clinic
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 25 (actual)
- Sponsor
- University of Glasgow · Academic / Other
- Sex
- All
- Age
- 1 Year – 16 Years
- Healthy volunteers
- Not accepted
Summary
This is a pilot study of children attending the Glasgow feeding clinic (GFC) which looks after a range of children with severe feeding problems who commonly have low appetite and extreme thinness. The investigators want to find out if these children are more likely to carry genetic markers of thinness.
Detailed description
Thinness occurs as a result of undereating, but it is not always clear why an individual child has not eaten enough, or how to get them to eat more. There is a need to understand the child characteristics that predispose to undereating and the how these operate, in order to design more effective treatment and prevention programmes. The Glasgow feeding clinic (GFC) looks after a range of children with severe feeding problems who commonly have low appetite and extreme thinness. The investigators want to find out if these children are more likely to carry genetic markers of thinness. The investigators will invite up to 60 families to complete a standardised online questionnaire (ICFET) about their child's eating behaviour and collect a saliva sample from their child, sent by post. The investigators will identify how many genetic markers for thinness each carries and relate this to their ICFET appetite scores and existing growth measurements as well as their feeding history.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Feeding clinic | These children have all attended a multidisciplinary feeding clinic with severe food refusal and were commonly receiving tube feeding or supplement drinks. The clinic helps children progress onto a normal oral diet |
Timeline
- Start date
- 2021-05-01
- Primary completion
- 2021-12-31
- Completion
- 2021-12-31
- First posted
- 2021-04-19
- Last updated
- 2022-04-07
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT04848129. Inclusion in this directory is not an endorsement.