Clinical Trials Directory

Trials / Completed

CompletedNCT04845048

Active Pharmacovigilance Study of Adsorbed COVID-19 (Inactivated) Vaccine

Active Pharmacovigilance Study of Post-vaccine Adverse Events of Sinovac's/ Butantan Institute Adsorbed COVID-19 (Inactivated) Vaccine

Status
Completed
Phase
Study type
Observational
Enrollment
2,549 (actual)
Sponsor
Butantan Institute · Other Government
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

This is a prospective cohort study, observational, multicentre, single-arm, post-registration to assess the safety of the Adsorbed COVID-19 (Inactivated) Vaccine Sinovac / Institute Butantan.

Detailed description

. This is a prospective cohort study, observational, multicentre, single-arm, post-registration to assess the safety of the Adsorbed COVID-19 (Inactivated) Vaccine Sinovac / Institute Butantan. * The immunization schedule is two doses intramuscular injections (deltoid) with a 14-28 days interval. * There will be 900 participants (300 health care professionals between 18 and 59 years old); 300 participants 75 years old or more; 300 participants between 60 and 74 years old. All participants must be allowed to receive the Adsorbed COVID-19 (inactivated) Vaccine according to the Brazilian Immunization National Plan. * For safety analysis , the incidence of adverse events after receiving the Adsorbed COVID-19 (inactivated) Vaccine that needed health assistance until 42 days after two-doses immunization schedule. * The total period of participation in the study will be approximately 60 days after completing the two-dose schedule of the vaccine. * Active pharmacovigilance studies are essential to assess the safety profile of the vaccine in subgroups that will be included as target populations in the Immunization Program.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAdsorbed COVID-19 (Inactivated) VaccineAdsorbed COVID-19 (inactivated) Vaccine manufactured by Sinovac/Butantan Institute

Timeline

Start date
2021-05-10
Primary completion
2023-03-12
Completion
2023-03-13
First posted
2021-04-14
Last updated
2023-05-22

Locations

3 sites across 1 country: Brazil

Source: ClinicalTrials.gov record NCT04845048. Inclusion in this directory is not an endorsement.