NCT04843488

Effectiveness of Different Membrane Applications in Vertical Ridge Augmentation

Effectiveness of Different Membrane Applications (Perforated Polytetrafluroethylene (PTFE) vs. Perforated PTFE+ Collagen Membrane) in Vertical Ridge Augmentation - Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Urban Regeneration Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This randomized clinical trial (RCT) study investigates if there is any difference in absolute vertical bone gain between perforated dense-polytetrafluroethylene (d-PTFE) mesh vs perforated d-PTFE mesh covered with a native collagen membrane. The primary endpoint is absolute vertical bone gain. The secondary endpoints are regeneration rate, complications rate, and pseudoperiosteum formation.

Conditions

• Bone Regeneration
• Dental Implants
• Polytetrafluoroethylene

Interventions

Type	Name	Description
PROCEDURE	Guided bone regeneration with a PTFE membrane	Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws.
PROCEDURE	Guided bone regeneration with a PTFE+collagen membrane	Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws and covered with a Collagen membrane subsequently.

Timeline

• Start date: 2021-04-15
• Primary completion: 2022-11-12
• Completion: 2023-05-02
• First posted: 2021-04-13
• Last updated: 2024-12-04

Locations

1 site across 1 country: Hungary