NCT04841070

NEURodevelopmental Outcome After Persistent Pulmonary Hypertension Of the Newborn

NEURodevelopmental Outcome in Children Between One and Five Years After Persistent Pulmonary Hypertension Of the Newborn

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 1 Year – 5 Years
• Healthy volunteers: Not accepted

Summary

Neonatal pulmonary hypertension is a rare but serious condition resulting from a lack of adaptation to extra-uterine life in some newborns. In the short term, the risk of death requires rapid and appropriate management of this transient pathology. In the long term, these newborns present a greater brain vulnerability, a consequence of the pathology itself with cerebral hypoxia but also invasive and aggressive therapies. Although current scientific evidence indicates a correlation with the existence of neurological developmental disorders, the understanding of the long-term neurological outcome of these babies remains poorly documented. Better knowledge of remote neuro-psychomotor development of the critical period

Conditions

• Persistent Pulmonary Hypertension of the Newborn

Interventions

Type	Name	Description
OTHER	Ages & Stages Questionnaires®, Third Edition (ASQ3)	Investigators will propose to parents of children hospitalized for the treatment of persistent pulmonary hypertension of the newborn a hetero-evaluation via the validated ASQ questionnaire to analyze neuro-psychomotor development.

Timeline

• Start date: 2021-07-25
• Primary completion: 2021-10-29
• Completion: 2021-10-29
• First posted: 2021-04-12
• Last updated: 2021-11-23

Locations

1 site across 1 country: France